BT3611 Bioinformatics Lab Syllabus:

BT3611 Bioinformatics Lab Syllabus – Anna University Regulation 2021

OBJECTIVES

 To provide a practical exposure to the bioinformatics databases, tools and software.
 To select and use functions in Perl for processing sequence data.

LIST OF EXPERIMENTS

1. Introduction to UNIX basic commands.
2. Perl programming and applications to Bioinformatics.
 Basic scripting.
 Regular expression101
 File i/o& control statement.
 Subroutines
 String specific functions.
3. Biological databases and their uses
 Sequence databases
 Structure databases
4. Sequence Analysis
 BLAST, FASTA
 Multiple sequence alignment
 ExPASy Tools
 DOTPLOT
5. Phylogenetic tree prediction
6. Protein secondary structure prediction
7. Protein tertiary structure prediction- Homology modeling using automated tool and Any open source software.
8. Lead molecule search using databases.
9. Protein-Ligand docking
10. Protein-Protein docking
11. ADMET modeling
12. Gene prediction tools.

TOTAL : 45 PERIODS

COURSE OUTCOMES:

Upon completion of this course,
Student will be able to

 Understand basic commans UNIX OS.
 Apply Perl programming to develop bioinformatics tools.
 Retrieve and analyze sequence and structure data.
 Access the databases and tools used for computer aided drug desgining.
 Compare and analyse biological sequences.
 Know the relationship of biomolecules from different species.