BT3002 Fermentation Technology Syllabus:

BT3002 Fermentation Technology Syllabus – Anna University Regulation 2021

COURSE OBJECTIVES

The student should be made to,
• Recognize the overall industrial fermentation process and the process flow sheet.
• Understand the knowledge on algal biotechnology.
• Interpret the knowledge on production of commercially important primary metabolites & secondary metabolites.
• Understand the biological effluent treatment process
• Apply the knowledge for the production of modern biological products.

UNIT I INTRODUCTION TO FERMENTATION

History and development of fermentation industry; General requirements of fermentation processes; types of fermentation – homo fermentation, hetero fermentation: category of fermentation based on end product formed – lactic acid fermentation, alcohol fermentation, acetic acid fermentation, butyric acid fermentation.

UNIT II ALGAL BIOTECHNOLOGY

Isolation, preservation and improvement of industrially important micro- organisms. Microorganisms and raw materials used for microbial Oil production, Current technologies of biofuel production −. Cyanobacterial and algal fuels; Fine chemicals and neutraceuticals from algae; UV absorbing pigments Industrial products from macro algae – seaweed biotechnology; Bioweapons and Bioshields.

UNIT III FUTURE ASPECTS OF FERMENTATION TECHNOLOGY

Microbial fungicides and Pesticides, Chemicals and Pharmaceuticals made by fermentation, Fermented food products – Beer, Wine, Genetically Modified Organisms, Biopolymers. Microbial
leaching, Effluent treatment using microbes, Future of fermentation technology and its products.

UNIT IV BIOLOGICAL EFFLUENT TREATMENT

Microbes involved in aerobic and anaerobic processes in nature; Water treatment- BOD, COD, dissolved gases, removal of heavy metals, total organic carbon removal; secondary waste water treatments; use of membrane bioreactor; aquaculture effluent treatment; Aerobic sludge and land fill leachate process; aerobic digestion.

UNIT V FERMENTATION PROCESS ECONOMICS

Process economics: General fermentation process economics; materials usage and cost; capital investment estimate; production cost estimate. Case studies –Traditional product and recombinant product; Bioprocess validation: Introduction, why validation, when does validation occur, validation structure, resources for validation, validation of systems and processes including SIP and CIP.

TOTAL 45 PERIODS

COURSE OUTCOMES

Upon completion of this course the student will be able to
1. Recall the basics of industrial fermentation and other processes.
2. Extend their knowledge on algal Biotechnology.
3. Extend their knowledge on commercial production of primary and secondary metabolites.
4. Extend their knowledge on the biological effluent treatment process.
5. Support for the commercial production of modern biological products.
6. Extend their knowledge on importance of fermentation process economics

TEXT BOOKS:

1. Peter F Stanbury, Allan Whitaker, Stephen J Hall. Principles of Fermentation Technology.(2016) Butterworth-Heinemann Press. UK.
2. H. J. Peppler, D. Perlman. Microbial Technology: Fermentation Technology.(2014). Academic Press.

REFERENCES:

1. T. El-Mansi, C. Bryce, Arnold L. Demain, A.R. Allman. Fermentation Microbiology and Biotechnology. Second Edition. (2006). CRC Press, USA.
2. Pandey A, Lasroche C, Soccol C. R and Dussop C. G. Advances in Fermentation technology (2008).Asiatech publishers Inc.
3. Peter,Max S. and Timmerhaus, Klaus D,Plant Design and Economics for Chemical Engineers,McGraw Hill.