BT3007 Bio-Nanotechnology Syllabus:
BT3007 Bio-Nanotechnology Syllabus – Anna University Regulation 2021
UNIT I NANOSCALE PROCESSES AND NANOMATERIALS
Overview of nanoscale processes and characterization of nanomaterials – Physicochemical properties of nanomaterials – Concepts in nanotechnology – Natural nanomaterials –Types of Nanomaterials (Quantum dots, Nanoparticles, Nanocrystals, Dendrimers, Polymeric nanoparticles, Buckyballs, Nanotubes)–Synthesis and assembly of nanoparticles and nanostructures using bioderived templates.
UNIT II STRUCTURAL AND FUNCTIONAL PRINCIPLES OF BIONANOTECHNOLOGY
Biomolecular structure and stability – Protein folding – Self-assembly – Self-organization – Information-Driven nanoassembly – Biomaterials – Biomolecular motors – Traffic across membranes – Biomolecular sensing – Self-replication – Machine-phase bionanotechnology.
UNIT III PROTEIN-BASED NANOTECHNOLOGY
Overview of protein nanotechnology – Nanotechnology with S-Layer protein – Engineered nanopores – Bacteriorhodopsin and its potential – Protein assisted synthesis of metal nanoparticles – Synthesis of protein-based nanoparticles – Protein nanopaticle-hybrids – Covalent and non-covalent protein nanoparticle conjugates – Protein-carbon nanotube conjugates.
UNIT IV DNA-BASED NANOTECHNOLOGY
DNA-based nanostructures – Biomimetic fabrication of DNA based metallic nanowires and networks – Self assembling DNA structures – DNA-nanoparticle conjugates – DNA-carbon nanotube conjugates – DNA templated electronics – DNA nanostructures for mechanics and computing – DNA nanomachine.
UNIT V APPLICATIONS OF NANOTECHNOLOGY
Promising nanobiotechnologies for applications in medicine –Liposomes in nanomedicine – Therapeutic applications of nanomedicine – Nano-Sized carriers for drug delivery and drug carrier systems – Protein and peptide nanoparticles, DNA based nan oparticles, Lipid matrix nanoparticles for drug delivery – Nanobiosensors for imaging and diagnosis.
TOTAL: 45 PERIODS
COURSE OUTCOMES
After completion of this course, the students should be able
To recognize the nanoscale processes and nanomaterials
To relate the structural and functional principles
To develop the protein based nanomaterials
To construct the DNA based nanomaterials
To apply the theoretical knowledge for the development of nanomedicine and nanosensors
To develop the nanomaterials based process and products
TEXT BOOKS
1. Niemeyer, C.M. and Mirkin, C.A., “Nanobiotechnology: Concepts, Applications and Perspectives”, Wiley- VCH, 2006.
2. Goodsell, D.S., “Bionanotechnology”, John Wiley and Sons, 2004.
REFERENCES
1. Shoseyov, O. and Levy I., “Nanobiotechnology: Bioinspired Devices and Materials of the Future”, Humana Press, 2008.
2. Gazit, E., and Mitraki, A., “Plenty of Room for Biology at the Bottom: An Introduction to Bionanotechnology”, Imperial College Press, 2013.
3. Jesus M. de la Fuente and Grazu, V., “Nanobiotechnology: Inorganic Nanoparticles Vs Organic Nanoparticles” Elsevier, 2012.