CBM332 Artificial Organs and Implants Syllabus:
CBM332 Artificial Organs and Implants Syllabus – Anna University Regulation 2021
COURSE OBJECTIVES:
The student should be made to:
To have an overview of artificial organs & transplants
To describe the principles of implant design with a case study
To explain the implant design parameters and solution in use
To study about various blood interfacing implants
To study about soft tissue replacement and hard tissue replacement
UNIT I ARTIFICIAL ORGANS & TRANSPLANTS
ARTIFICIAL ORGANS:-Introduction, outlook for organ replacements, design consideration, evaluation process.
TRANSPLANTS:-Overview, Immunological considerations, Blood transfusions, individual organs – kidney, liver, heart and lung, bone marrow, cornea.
UNIT II PRINCIPLES OF IMPLANT DESIGN
Principles of implant design, Clinical problems requiring implants for solution, Permanent versus absorbable devices, the missing organ and its replacement, Tissue engineering, scaffolds, cells and regulators criteria for materials selection, Case study of organ regeneration.
UNIT III IMPLANT DESIGN PARAMETERS AND ITS SOLUTION
Biocompatibility, local and systemic effects of implants, Design specifications for tissue bonding and modulus matching, Degradation of devices, natural and synthetic polymers, corrosion, wear and tear, Implants for Bone, Devices for nerve regeneration.
UNIT IV BLOOD INTERFACING IMPLANTS
Neural and neuromuscular implants, heart valve implants, heart and lung assist devices, artificial heart, cardiac pacemakers, artificial kidney- dialysis membrane and artificial blood.
UNIT V IMPLANTABLE MEDICAL DEVICES AND ORGANS
Gastrointestinal system, Dentistry, Maxillofacial and craniofacial replacement, Soft tissue repair, replacement and augmentation, recent advancement and future directions.
COURSE OUTCOMES:
On successful completion of this course, the student will be able to
CO1: Gain adequate knowledge about artificial organs & transplants
CO2: Get clear idea about implant design and its parameters and solution
CO3: Have in-depth knowledge about blood interfacing implants
CO4: Explain different types of soft tissue replacement and hard tissue replacement
CO5: Assess compatibility and functioning of artificial organs inside the living system.
TOTAL:45 PERIODS
TEXT BOOK
1. Kopff W.J, Artificial Organs, John Wiley and sons, New York, 1st edition, 1976
REFERENCES
1. J D Bronzino, Biomedical Engineering handbook Volume II, (CRC Press / IEEE Press), 2000.
2. R S Khandpur, Handbook of Biomedical Instrumentation,Tata McGraw Hill, 2003
3. Yannas, I. V, “Tissue and Organ Regeneration in Adults”, New York, NY: Springer, 2001. ISBN:9780387952147.
4. John Enderle, Joseph D.Bronzino, Susan M.Blanchard, “”Introduction to Biomedical Engineering”, Elsevier, 2005.