CBM359 Neural Engineering Syllabus:
CBM359 Neural Engineering Syllabus – Anna University Regulation 2021
COURSE OBJECTIVES:
The student should be made to:
To be familiar with the nervous system development
To be exposed to neuronal diseases and disorders
To be familiar with nerve reconstruction and repairing
UNIT I BASICS OF NEURON STRUCTURE AND FUNCTIONS
Nervous system development. Trophic factors, extra cellular matrix components in nervous system development. Neuron: structure – function – classification. Glial cells – myelination. Neurotransmitter – types and functions. Synapses – Transport of materials and impulse in neurons.
UNIT II BRAIN, BRAIN STEM AND SPINAL CORD
Brain: structures – lobes – functional areas. Brain stem: structures – functional areas. Spinal cord: structure – functions. Concepts of nuclei – sensory and motor Tracts – Reticular formation. Blood supply to Brain and spinal cord.
UNIT III NEURONAL DISEASES AND DISORDERS
Neuro degeneration: Degenerative, Demyelinated and injury related disorders associated with nervous system. Wallerian Degeneration. Neuronal plasticity – CNS acting drugs and their pharmacokinetics. Alzheimer‘s, Parkinson‘s and Prion diseases
UNIT IV NEUROPHYSIOLOGY & NEURORADIOLOGY
Physiology of nerve conduction. Peripheral nerves – structure & Functions. Synaptic transmission and cellular signaling of Neurons. Electrical activity of the Brain and recording of brain waves. Evoked potentials. Visualization of nervous system. Neuromotor-machine interface: human voluntary motor control system.
UNIT V NERVE RECONSTRUCTION AND REHABILITATION
Neural plasticity; Neurological dysfunctions – Regeneration of the peripheral nervous system. Neural tissue engineering; Nerve graft; Drug delivery system in CNS. Rehabilitation: Mechanisms for Neuromotor rehabilitation; Robotics and virtual reality in physical therapy; Transcranial magnetic stimulation
COURSE OUTCOMES:
On successful completion of this course, the student will be able to
CO1: Explain the basic structure and functions of human nervous system.
CO2: Understand diseases and degeneration related to nervous system.
CO3: Analyze visualization and radiological assessment of nervous system.
CO4: Apply neural tissue engineering for rehabilitation.
CO5: Discuss about Regeneration of nervous system.
TOTAL:45 PERIODS
TEXT BOOKS
1. Mathews G.G., “Neurobiology”, 2nd edition, Blackwell Science, UK, 2000
2. Malcom Carpenter, “Textbooks of Neuroanatomy”, Mc. Graw hill Edition, 1996
REFERENCES
1. W. Mark Saltzman, “Tissue Engineering – Engineering principles for design of replacement organs and tissue’’, Oxford University Press Inc New York, 2004.
2. Park J.B., “ACS Biomaterials Science and Engineering”, Plenum Press, 2014. Saunders, 2006.