BM3491 Biomedical Instrumentation Syllabus:
BM3491 Biomedical Instrumentation Syllabus – Anna University Regulation 2021
COURSE OBJECTIVES:
● To understand the origin of various biological signals and electrode configurations specific to bio-potential measurements.
● To understand the characteristics of Bio signals.
● To understand the design of bioamplifiers
● To explain the different techniques used for measurement of non-electrical bioparameters
● To explain the biochemical measurement techniques as applicable for diagnosis and treatment.
UNIT I ELECTRODE CONFIGURATIONS
Bio signals characteristics – Origin of bio potential and its propagation. Frequency and amplitude ranges. Electrode configurations: Electrode-electrolyte interface, electrode–skin interface impedance, polarization effects of electrode – non-polarizable electrodes. Unipolar and bipolar configuration, classification of electrodes.
UNIT II BIOSIGNAL CHARACTERISTICS
Bio signals characteristics – ECG-frequency and amplitude ranges – Einthoven’s triangle, standard 12 lead system. EEG – EEG – 10-20 electrode system, unipolar, bipolar and average mode. EMG– unipolar and bipolar mode. EMG – Electrode configuration -unipolar and bipolar mode.
UNIT III BIOAMPLIFIERS
Need for bio-amplifier – Differential bio-amplifier – Single ended amplifier – Band pass filtering, isolation amplifiers – transformer and optical isolation – isolated DC amplifier and AC carrier amplifier. Chopper amplifier. Power line interference
UNIT IV MEASUREMENT OF BIO SIGNALS
Temperature, respiration rate and pulse rate measurements. Blood Pressure – indirect methods: auscultatory method, oscillometric method, direct methods: electronic manometer, Pressure amplifiers – systolic, diastolic, mean detector circuit. Blood flow and cardiac output measurement: Indicator dilution, thermal dilution and dye dilution method, Electromagnetic and ultrasound blood flow measurements
UNIT V BIOCHEMICAL MEASUREMENTS
Biochemical sensors – pH, pO2 and pCO2, Ion selective Field effect Transistor (ISFET), Immunologically sensitive FET (IMFET), Blood glucose sensors. Blood gas analyzers, colorimeter, flame photometer, spectrophotometer, blood cell counter, auto analyzer.
COURSE OUTCOMES:
On successful completion of this course, the student will be able to
CO1 : Illustrate the origin of various biological signals and their characteristics.
CO2: Gain knowledge on characteristics of bio signals.
CO3: Gain knowledge on various amplifiers involved in monitoring and transmission of biosignals.
CO4: Explain the different measurement techniques for non-electrical bio-parameters
CO5: Explain the biochemical measurement techniques as applicable for diagnosis and further treatment.
TOTAL: 45 PERIODS
TEXT BOOKS:
1. Leslie Cromwell, “Biomedical Instrumentation and measurement”, 2nd edition, Prentice hall of India, New Delhi, 2015.
2. John G. Webster, “Medical Instrumentation Application and Design”, 4th edition, Wiley India Pvt Ltd, New Delhi, 2015.
3. Khandpur R.S, “Handbook of Biomedical Instrumentation”, Tata McGraw Hill, New Delhi, 2003.
REFERENCE BOOKS
1. John Enderle, Susan Blanchard, Joseph Bronzino, “Introduction to Biomedical Engineering”, second edition, Academic Press,2005.
2. Joseph J. Carr and John M. Brown, “Introduction to Biomedical Equipment Technology”, Pearson Education, 2004.