BM3252 Medical Physics Syllabus:

BM3252 Medical Physics Syllabus – Anna University Regulation 2021

COURSE OBJECTIVE:

 To provide understanding of the application of the radiation concepts and methods of Physics in Medical science
 To accentuate the principle, effects and clinical applications of ionizing, non-ionizing and electromagnetic radiation.
 To enunciate the fundamentals of acoustic waves and their interaction with human tissues.
 To explore the effects of radiation in matter and how isotopes are produced
 To study effects of sound and light in human body

UNIT I LOW ENERGY ELECTROMAGNETIC SPECTRUM AND ITS MEDICAL APPLICATION

Physics of light, Intensity of light, limits of vision and color vision an overview, Non-ionizing Electromagnetic Radiation: Overview of non-ionizing radiation effects-Tissue as a leaky dielectric-Low Frequency Effects- Higher frequency effects., Thermography– Application

UNIT II PRINCIPLES OF RADIOACTIVE NUCLIDES

Radioactive Decay – Spontaneous Emission – Isometric Transition – Gamma ray emission, alpha, beta, Positron decay, electron capture, Sources of Radioisotopes Natural and Artificial radioactivity, Radionuclide used in Medicine and Technology, Decay series, Production of radionuclides – Cyclotron produced Radionuclide- Reactor produced Radionuclide-fission and neutron capture reaction, radionuclide Generator-Technetium generator

UNIT III INTERACTION OF RADIATION WITH MATTER LIPIDS

Interaction of charged particles with matter –Specific ionization, Linear energy transfer range, Bremsstrahlung, Annihilation, Interaction of X and Gamma radiation with matter- Photoelectric effect, Compton Scattering , Pair production, Attenuation of Gamma Radiation, Interaction of neutron with matter and their clinical significance

UNIT IV RADIATION DOSE AND ITS EFFECTS

Dose and Exposure measurements – Units (SI), Inverse square law, Maximum permissible exposure, relationship between the dosimetric quantities, Radiation biology – effects of radiation, concept of LD 50, Stochastic and Non-stochastic effects, Radiation Syndrome.

UNIT V PRINCIPLES AND APPLICATIONS OF SOUND IN MEDICINE

Physics of sound, Normal sound levels, ultrasound fundamentals, Generation of ultrasound (Ultrasound Transducer), Interaction of Ultrasound with matter- Cavitations, Reflection, Transmission, Scanning methods, Artifacts, Ultrasound- Doppler effect, Clinical Applications

TOTAL : 45 PERIODS

COURSE OUTCOMES:

Upon completion of the course, students will be able to:
CO1:Interpret the properties of electromagnetic radiations and its effect on human.
CO2:Apply the principles and understand the production of radioactive nuclides.
CO3:Explain the interaction of radiation with matter.
CO4:Identify and Analyse the radiation quantities and its effects
CO5:Demonstrate the knowledge on the properties of sound and its application in medicine.

TEXT BOOKS:

1. B.H. Brown, R.H. Smallwood, D.C. Barber, P.V. Lawford, D.R. Hose, “Medical Physics and Biomedical Engineering”, Institute of physics publishing, Bristol and Philadelphia, 1999.
2. Gopal B. Saha “Physics and Radiobiology of Nuclear Medicine” Fourth edition Springer, 2006.

REFERENCES:

1. W.J. Meredith and J.B. Massey “Fundamental Physics of Radiology” Varghese Publishing house, Third Edition, 2013.
2. Steve Webb, The Physics of Medical Imaging, Taylor & Francis, Newyork, Second Edition, 2012.
3. R.S. Khandpur, “Handbook of Biomedical Instrumentation”, Tata McGraw-Hill, New Delhi, 2003.

e-RESOURCES:

1. http://www.nptel.ac.in/courses/115102017/ , “Nuclear science and Engineering”, Dr. Santanu Gosh, Department of Physics, IIT, Delhi.
2. http://www.uthgsbsmedphys.org/GS02-0093/ ,” Introduction to Medical Physics”, Dr George Starkschall, The University of Texas at Houston.