BT3491 Chemical Process Calculations in Biotechnology Syllabus:

BT3491 Chemical Process Calculations in Biotechnology Syllabus – Anna University Regulation 2021

COURSE OBJECTIVES:

 To enable the students to learn about basic concepts of chemical process and calculations
 The course aims to develop skills of the students in the area of Chemical Engineering with emphasis in process calculations and fluid mechanics.
 The course will enable the students to perform calculations pertaining to processes and operations.

UNIT I BASIC CHEMICAL CALCULATIONS

Dimension – Systems of units esp. engineering FPS, Engineering MKS & SI systems – Conversion from one system to the other – composition of mixtures and solutions – mass fraction, mass %, mole fraction, mole %, mass ratios, molarity, molality, normality, ppm, composition by density.

UNIT II IDEAL AND ACTUAL GAS EQUATIONS

Ideal and actual gas equations, Vander Walls, compressibility factor equations, Application to pure gas & gas mixtures – partial pressures, partial volumes – Air-water vapour systems, Humidity, Molar Humidity, Relative Humidity, % Saturation, humid Volume – Humidity chart – wet, Dry bulb, Dew point temperatures, pH of solutions, Vapour pressure.

UNIT III MATERIAL BALANCE

Material balance concept – overall & component – material balance applications for evaporator, gas absorber without reaction, Distillation (Binary system), Liquid extraction, solid-liquid extraction, drying, crystallization, Humidification, Reverse Osmosis separation and Mixing Recycle and Bypass illustration

UNIT IV ENERGY BALANCE

General energy balance equation for open systems, closed system sensible heat calculation, Heat required for phase change thermo chemistry, application of steam tables, Saturated and
superheated steam application in bioprocess

UNIT V CHEMICAL REACTION

Chemical Reaction-Limiting, excess component, Fractional conversion, Percent conversion, Fractional yield in multiple reactions. Simple problems, Combustion Reactions.

TOTAL : 45 PERIODS

COURSE OUTCOMES:

Upon success completion of this course, the students will be able to:
1. To recite the basics of enzyme and principles of catalysis
2. To understand the enzyme kinetics and various enzyme kinetic models
3. To gain the knowledge to develop the enzyme immobilization and biosensors
4. To analyze and learn enzyme reactions for the production and purification process
5. To give the student a basic knowledge concerning biotransformation reactions with the usage of enzymes
6. To apply the skills for the development of processes and products

TEXT BOOKS:

1. 1. Bhatt B.I & SB Thakore, Stoichiometry – Fifth edition Tata McGraw Hill 2017
2. K.A.Kavhane, Introduction to Process calculations,Nirali Publishers,1st Edition,2016
3. Himmelblau D.M “Basic principles & Calculations in Chemical Engineering” 8th edn PHI 2014.

REFERENCES:

1. McCabe W.L & J.C.Smiith & P.Harriot “Unit operations of chemical Engineering” 7th Edn McGraw Hill 2017
2. S. Pushpavanam, Introduction to Chemical Engineering, PHI Learning Pvt. Ltd.,2012
3. Geankoplis C.J. “Transport process & Separation process Principles 4th edition-PHI 2006.