BT3301 Biochemical Thermodynamics Syllabus:

BT3301 Biochemical Thermodynamics Syllabus – Anna University Regulation 2021

COURSE OBJECTIVE:

• To enable the students to learn about basic concepts of classical and statistical Thermodynamics
• Apply the knowledge on Phase equilibrium and chemical reaction equilibrium.

UNIT I THERMODYNAMIC LAW AND PROPERTIES OF FLUIDS

First Law of thermodynamics, a generalized balance equation and conserved quantities, Volumetric properties of fluids exhibiting non ideal behavior; residual properties; estimation of thermodynamic properties using equations of state; calculations involving actual property exchanges; Maxwell’s relations and applications.

UNIT II SOLUTION THERMODYNAMICS

Partial molar properties; concepts of chemical potential and fugacity; ideal and non-ideal solutions; concepts and applications of excess properties of mixtures; activity coefficient; composition models; Gibbs Duhem equation.

UNIT III PHASE EQUILIBRIA

Criteria for phase equilibria; VLE calculations for binary and multi component systems; liquid-liquid equilibria and solid-solid equilibria.

UNIT IV CHEMICAL REACTION EQUILIBRIA

Equilibrium criteria for homogeneous chemical reactions; evaluation of equilibrium constant; effect of temperature and pressure on equilibrium constant; calculation of equilibrium conversion and yields for single and multiple reactions.

UNIT V THERMODYNAMIC DESCRIPTION OF MICROBIAL GROWTH AND PRODUCT FORMATION

Thermodynamics of microbial growth stoichiometry thermodynamics of maintenance, Calculation of the Operational Stoichiometry of a growth process at Different growth rates, Including Heat using the Herbert –Pirt Relation for Electron Donor, thermodynamics and stoichiometry of Product Formation

TOTAL: 45 PERIODS

COURSE OUTCOMES:

Upon completion of this course the student will be able to
 To explain the theoretical concepts of thermodynamics and how it applies to energy Conversion.
 To demonstrate the capability to analyse the energy conversion performance in a variety of modern applications in biological systems.
 To design and carry out bioprocess engineering experiments, and analyse and interpret fundamental data to do the design and operation of bioprocesses.
 To describe the criteria when two phases coexist in equilibrium and the vapour liquid equilibrium calculations.
 To understand the microbial growth and product formation and its kinetics.
 To explore the thermodynamic concepts in bio chemical engineering.

TEXT BOOKS:

1. Smith J.M., Van Ness H.C., and Abbot M.M. “Introduction to Chemical Engineering Thermodynamics”, VIth Edition. Tata McGraw-Hill, 2003.
2. Narayanan K.V. “A Text Book of Chemical Engineering Thermodynamics”, PHI, 2003.
3. Christiana D. Smolke, “ The Metabolic Pathway Engineering Handbook Fundamentals”, CRC Press Taylor & Francis Group, 2010.

REFERENCE:

1. Sandler S.I. “Chemical and Engineering Thermodynamics”, John Wiley,1989.